Maybe too late, but you could use an !if depending on e.g. -DLEFT_TO_RIGHT
e.g. you could use following sample.puml diagram
@startuml
!if %variable_exists("LEFT_TO_RIGHT")
left to right direction
!endif
user1 --> (Usecase 1)
user2 --> (Usecase 2)
@enduml
and start it with or without -DLEFT_TO_RIGHT
java -jar plantuml.jar -DLEFT_TO_RIGHT sample.puml
java -jar plantuml.jar sample.puml
BR Helmut